Ponta do Lobo is a headland in the southeastern part of the island of Santiago, Cape Verde.

It is in the municipality of São Domingos, 4 km east of Vale da Custa, 4 km southeast of Moia Moia and 11 km northeast of Praia.

The nearby bay Porto Lobo was mentioned as P. Lobo on the 1747 map by Jacques-Nicolas Bellin.

[1] The Ponta do Lobo Lighthouse stands on the headland.

[2] This Cape Verdean location article is a stub.