The pontine nuclei (or griseum pontis) are all the neurons of the ventral pons.

Corticopontine fibres project from the primary motor cortex to the ipsilateral pontine nucleus; pontocerebellar fibers then relay the information to the contralateral cerebellum via the middle cerebellar peduncle.

[citation needed] The pontine nuclei encompass all of the about 20 million neurons scattered throughout the basilar part of pons.

[citation needed] Corticopontine fibres arise primarily from the neocortex layer V of the premotor, somatosensory, non-striate visual, posterior parietal, and cingulate cerebral cortex; there are also a few fibers originating from the prefrontal, temporal, and striate cortex.

[1] Pontocerebellar fibers are the sole efferent pathway of the pontine nuclei.