Porina heterospora is a species of corticolous (bark-dwelling), crustose lichen in the family Porinaceae.

The species was first described in 1933 as a variety of Porina nucula, when Joyce Hedrick published Bruce Fink's description based on a type specimen collected in Florida by William Wirt Calkins.

The description was among the unpublished materials left by Fink upon his death in 1927, which Hedrick, his former student, later brought to publication.

[3] Patrick McCarthy considered it to be a synonym of the saxicolous (rock-dwelling) species Porina guaranitica in a 1993 work,[4] but the differences in spore structure and size between the two are significant.

[5] Porina heterospora is common throughout the Southern Coastal Plain, having first been reported from Florida and later discovered in Louisiana[3] and Alabama.