Porokeratosis is a specific disorder of keratinization that is characterized histologically by the presence of a cornoid lamella, a thin column of closely stacked, parakeratotic cells extending through the stratum corneum with a thin or absent granular layer.

[1]: 532 Porokeratosis may be divided into the following clinical types:[1]: 532 Linear porokeratosis has been associated with mutations in the PMVK and MVD genes.

[7] The PMVK gene encodes the enzyme phosphomevalonate kinase and the MVD gene encodes the enzyme diphosphomevalonate decarboxylase.

Porokeratosis has a characteristic histomorphologic feature known as a cornoid lamella.

Dermabrasion