Port Rex Technical High School (Afrikaans: Hoër Tegnise Skool Port Rex) is a public boarding co-educational and day school in Berea, East London in the Eastern Cape province of South Africa.

The name "Port Rex" came from the British sailor who landed at the Buffulo River mouth in 1823 .

By early 1980s, the premises in Lukin Road had become too cramped to house three separate educational institutions.

The De La Salle College (1935-1976) in Chamberlain Road became available and was bought from the Irish Catholic Brothers for R 6 million .

Dr Brittz was again influential in negotiations with the Public Works Department so that the property was allocated to Port Rex THS.