The patient can be placed inside the bag, which is then sealed and inflated with a foot pump.
Within minutes, the effective altitude can be decreased by 1000 m to as much as 3000 m (3281 to 9743 feet) depending on the elevation.
Igor Gamow originally designed a predecessor to the Gamow bag called "The Bubble" to study the effect of high altitude on stamina and performance in athletes.
Gamow later re-designed "The Bubble" into a bag that could be used in high-altitude wilderness.
[4] Like office-based hyperbaric medicine, the Gamow bag uses increased partial pressure of oxygen for therapy of hypobaric injury but has the advantage of portability for field use.