Located on St. John Street, it was demolished in 1961 and is now the site of a strip mall.

[1] The union station opened on June 25, 1888, serving trains of the Boston and Maine, Maine Central, and Portland and Ogdensburg railroads,[2] although the Grand Trunk Railway continued to use a different station two miles away on India Street.

[4] On August 31, 1961, the train station was demolished, and a strip mall built on the property.

[6][7] Preservation group Greater Portland Landmarks was formed in 1964, in response to the station's demolition.

[8] Noteworthy trains into the 1950s and in some cases to 1960:[9][10] A proposal to move Amtrak's Downeaster service from the Portland Transportation Center to a site near Union Station's original location has been endorsed by the Maine Department of Transportation.