The eastern end of the line is at Hinkle, Oregon, where it meets the La Grande Subdivision.

The line continues across the Willamette over the Steel Bridge to Union Station.

[1] As of 2022[update], the Portland Subdivision hosts no passenger traffic, save for the small section in Portland from Union Station across to the Steel Bridge to the Brooklyn Subdivision.

[2] This hosts Amtrak Cascades and Coast Starlight, both of which operate between Portland and Eugene.

[3] The Pioneer, discontinued in 1997, provided service over the whole route, including stops in Hood River, the Dalles, and Hinkle.