It was part of the Spanish royal collection and is now in the Museo del Prado, in Madrid.
The portrait follows a classic scheme already used by Raphael and Leonardo da Vinci, in which the model sits next to a window opening on a landscape.
The landscape gives depth to the composition, and its greenish and bluish tones provide a contrast to the interior scene dominated by warm colors.
The figure shows some stiffness, possibly related to the concept of majesty as used in imperial iconography.
She wears a rich red dress and gold brocade and trimmed with rhinestones.