Portrait of Spencer Compton is a c. 1710 portrait painting of the English politician Spencer Compton by the German-born British artist Godfrey Kneller.

[1] Compton was a Whig supporter of Robert Walpole, widely accredited as the first formal British prime minister.

In 1730 he was appointed Lord President of the Council and elevated to be Earl of Wilmington.

He succeeded Walpole as prime minister in 1742, but his administration lasted less than seventeen months before his death in 1743; he was replaced by his colleague and fellow Whig Henry Pelham.

Today it is in the collection of the National Portrait Gallery, London.