The eastern part of the municipal territory with the Březno village lies in the Lower Ohře Table.

A distinctive geologic outcrop of the Cretaceous period called Březenské souvrství is located near the village of Březno.

A Benedictine monastery with the Church of the Blessed Virgin Mary was founded here probably at the end of the 11th century.

It was built near the site where a former Slavic gord called Drahúš on the Ohře river had been erected at the behest of the Přemyslid dukes.

During their rule, the settlement prospered, and in 1510, it obtained town privileges by King Vladislaus II.

When the region returned to the Czechoslovak Republic at the end of World War II, the remaining 'Sudeten German' population was expelled according to the Beneš decrees.

Outrages culminated in a massacre on 3–7 June 1945, when about 800 German civilians, mainly men who had been deported to Postoloprty from nearby Žatec, were tortured and shot.