Potosí (Spanish pronunciation: [potoˈsi]; Quechua: P'utuqsi; Aymara: Putusi) is a department in southwestern Bolivia.

It is a mostly barren, mountainous region with one large plateau to the west, where the largest salt flat in the world, Salar de Uyuni, is located.

Cerro Potosí was the richest province in the Spanish Empire, providing a great percentage of the silver that was shipped to Europe.

[3] Shortly after the strike an agreement with the central government was reached, stipulating the construction of motorways and a cement plant and further discussions about mining conditions.

The current governor, Jhonny Mamani of the Movement for Socialism – Political Instrument for the Sovereignty of the Peoples was elected on 7 March 2021.