The canyon begins in northern Rocky Mountain National Park, at an elevation of approximately 9,000 ft (2,700 m), where the Poudre descends from near the continental divide.
It winds gently to the northeast, then east, descending the slope of the Colorado Tertiary Pediment, emerging through the southern end of the Laramie Foothills north of Bellvue at an elevation of approximately 5,000 ft (1,500 m).
The flanks of the canyon wall are gently sloping and forested along most of its length, with the exception of several "narrows", at which the river has carved through recent formations leaving behind large glacial debris.
The relative isolation of the canyon compared to ones further south along the Colorado Front Range gives a tranquil atmosphere with only small-scale tourist enterprises.
The commercial establishments, notably in Poudre Park, cater mostly to local clientele except during the fishing and whitewater rafting season, when the canyon receives a modest number of regional and national visitors.