He also served as the Chief Minister of West Bengal in the "Progressive Democratic Alliance Front" government from 21 November 1967 to 20 February 1968.

Prafulla had very rural upbringing and enjoyed cultural festivals such as Jatra, Kirtan, Padavali Gan, and also participated in agricultural activities.

[7] Ghosh developed an interest in the Swadeshi Movement early on, but was most impressed and inspired by the ideas of armed revolution propagated by the Dhaka Anushilan Samiti, which he joined in 1909.

However, the methods of the Samiti for raising money through theft and then defending the same in Court eventually alienated him, and he finally quit in 1913 to focus on academia.

[8] His great-granddaughter is Priyanka Yoshikawa, who won the 2016 Miss World Japan contest, and his only grandson was Saumya Ghosh, Supreme Court and Inner Temple Bar-at-Law.