Prasanna Acharya (born 8 August 1949) is an Indian politician from Odisha, India.

In May 2009 Prasanna Acharya stood for election to the Odisha Assembly again rather than for the national parliament.

In the 2014 Odisha Legislative Assembly election Prasanna Acharya lost to Subal Sahu of Indian National Congress by a margin of 458 votes from Bijepur.

In 2019 Prasanna Acharya lost to Suresh Pujari of Bharatiya Janata Party in Loksabha election from Bargarh.

Acharya also held the post of the Minister of Finance, Health, Rural Development etc in Odisha.