Currently he's working as a Member of State Planning Board, Government of Odisha with a Cabinet Minister status.

Patasani joined the Maharishi Mahesh Yogi ashram at Rishikesh and went through yoga ashanas trainings.

Around 1980's he returned to India and was the founder President of Maharishi College of Natural Law in Bhubaneswar, the state capital of Orissa.

In 1980s the people of the eastern region used to travel towards the southern states for higher and technical educations, where after upon the active leadership of Prasanna Patasani not only the state of Orissa became the hub of the technical education in the state but also in the entire eastern region Orissa became the hub for the technical education behind almost all the institutions, Prasanna Patasani has played the major role for establishment of such institutions.

During the period of his underground he joined his guru, Maharishi Mahesh Yogi, who taught him the Patanjali Yoga Sutra, which changed his life.