[3] On Tuesday, 30 August 2022, the university was granted a Presidential Charter by President of Ghana Nana Akufo Addo.

[1][4] In 1848, the church founded a teacher-catechist seminary, the Basel Mission Seminary, later known as the Presbyterian Training College (PTC) at Akropong as the second higher educational institution in West Africa after Fourah Bay College in Sierra Leone.

[1][4] More than a century and a half later, the Synod of the Presbyterian Church during its 1996 conference voted to establish an actual university culminating in the setting up of an Implementation Committee in 1998.

[1][4] Despite its religious affiliation, the university college welcome students of all backgrounds, ethnicity, religion and geography.

[1][4] The school runs a fee-paying, multi-campus, residential or hostel system in partnership with private enterprise.