In 2005, the Hall's doors were closed for a period of time due to Hurricane Katrina, but the band continued to tour.

Allan Jaffe was a tuba player who had graduated from the Wharton School of Business in Philadelphia, while his wife had been employed at an advertising agency.

Dejan's Olympia Brass Band was featured in Fat Tuesday and All That Jazz, in addition to the Arthur Hall Afro-American Dance Ensemble of Philadelphia, Pennsylvania.

[1] Ben Jaffe toured with the Preservation Hall Jazz Band, playing double bass and tuba.

Most notable among the former were Michael White (ii), Wendell Brunious (who gradually took over the leadership of Valentine's band in the elder trumpeter's final years, as well as the touring band), Freddie Lonzo, and the tuba player Walter Payton; Europeans included the Swedish pianist Lars Edegran, the English trumpeter Clive Wilson, Orange Kellin, and Jacques Gauthé" (Hazeldine, Kernfeld).

Nearing Preservation Hall's 45th anniversary, the band collaborated with musicians from other genres, such as Blind Boys of Alabama on their Grammy Award winning album Down in New Orleans.

The album American Legacies was a collaboration with the Del McCoury band, uniting New Orleans jazz and bluegrass music.

In 2014, the Preservation Hall Jazz Band made a guest appearance on the Foo Fighters' eighth studio album Sonic Highways.

A writer for the NEA commented, "Whether performing at Carnegie Hall or Lincoln Center, for British Royalty or the King of Thailand, the band conveys a joyful, timeless spirit.

Under the auspices of current director, Ben Jaffe, the son of founders Allan and Sandra, Preservation Hall continues with a deep reverence and consciousness of its impressive history as a venue, band, and record label.