She was the Bharatiya Janata Party (BJP)-led National Democratic Alliance (NDA) nominee and defeated the United Opposition nominee and former Minister of Finance, Yashwant Sinha.

Prior to being the presidential nominee, she was the Governor of Jharkhand and a minister in Odisha Government.

In June 2022, the BJP nominated Murmu as the National Democratic Alliance's candidate for President of India for the 2022 election.

[1] Murmu visited various states as part of the campaign around the country seeking support for her candidature, from BJP lawmakers and other opposition parties.

She visited NE states, the JMM party of Jharkhand, BJD of Odisha, Shiv Sena of Maharashta, BSP of Uttar Pradesh, JDS of Karnataka and many others were some of the prominent opposition parties that extended their support to her.