[3][4][5] Before the Symmes Purchase of the 1780s, the area of Price Hill was sparsely populated Indian territory.

Before Cincinnati annexed it beginning in 1870, Price Hill was divided between Delhi and Storrs townships.

Cincinnati became heavily populated in the 19th century, due to steamboat traffic and hog packing, and some of the city's wealthier residents settled in the nearly inaccessible hill country to the west.

One such resident was General Rees E. Price, who purchased and developed large parts of the hill.

With its base on the corner of 8th Street and Glenway Avenue, the Incline climbed 350 feet over the top of the hill.

[6] The Eighth Street Viaduct was built by the end of the century, and the more accessible region became a thriving upper-middle-class suburb, with a commercial center along Glenway Avenue.

Mount St. Mary's Seminary of the West was first established on a 10-acre (4.0 ha) site at the northwest corner of Grand and Warsaw Avenues.

The site was converted to a Catholic school devoted to the care and training of orphaned, dependent, and underprivileged girls.

Seton High School was founded as Mount St. Vincent Academy, Cedar Grove in 1854 by the Sisters of Charity of Cincinnati.

The city police use the Mill Creek as the border between Lower Price Hill and Queensgate.

[3] According to the U.S. Census American Community Survey, for the period 2016-2020 the estimated median annual income for a household in the neighborhood was $30,112.

[4] According to the U.S. Census American Community Survey, for the period 2016-2020 the estimated median annual income for a household in the neighborhood was $44,664.

[5] According to the U.S. Census American Community Survey, for the period 2016-2020 the estimated median annual income for a household in the neighborhood was $15,987.

[citation needed] There is a community newspaper called "Price Hill Press,"[8] which is published by The Cincinnati Enquirer.