Prideaux Selby (baptised 21 December 1747 – 9 May 1813) was an English soldier and political figure in Upper Canada.
He was born in Alnwick, Northumberland, England a son of the Holy Island branch of the Selby family.
In 1792, he was appointed assistant secretary of Indian Affairs by Lieutenant Governor John Graves Simcoe and took up residence in Amherstburg.
In 1802, he became a justice of the peace in the Western District.
His son, also Prideaux Selby was born in London and ultimately inherited family estates at Swansfield House, Alnwick and Pawston, Northumberland.