CIS Member State This is a list of prime ministers of Uzbekistan (Uzbek: O‘zbekiston bosh vaziri), from the establishment of the office in 1925 as the chairman of the Council of Ministers of the Uzbek SSR to the present day.

The Government House on Mustakillik Square in Tashkent serves as the Prime Minister's primary workplace and residence.

The Prime Minister engages in negotiations, signs intergovernmental treaties, agreements, and memoranda, subject to the president's approval.

Responsibilities also include the allocation of duties among deputy prime ministers, making decisions on non-Cabinet meeting matters related to state and economic management, and proposing Cabinet members to the president after Legislative Chamber approval.

Additionally, the Prime Minister suggests appointments and dismissals of regional governors to the president, coordinates the activities of government bodies, resolves disagreements, and presents an annual report to both chambers of the Oliy Majlis on socio-economic development and priorities.