Medical professionals typically diagnose the fetus as being small for gestational age, or as showing intrauterine growth restriction when an ultrasound is conducted.
After birth, growth continues at a much slower rate, leaving individuals with primordial dwarfism perpetually years behind their peers in stature and in weight.
[2] In the case of microcephalic osteodysplastic primordial dwarfism type II (MOPDII), there can be increased risk of vascular problems, which may cause premature death.
Children with RSS that are treated with growth hormone before puberty may achieve several inches of additional height.
In January 2008, it was published that mutations in the pericentrin gene (PCNT) were found to cause primordial dwarfism.