[1] Feingold syndrome is marked by various combinations of microcephaly, limb malformations, esophageal and duodenal atresias.

Cognition is affected, and ranges from below-average IQ to mild intellectual disability.

[2] Feingold syndrome is caused by mutations in the neuroblastoma-derived V-myc avian myelocytomatosis viral-related oncogene (MYCN) which is located on the short arm of chromosome 2 (2p24.1).

This syndrome has also been linked to microdeletions in the MIR17HG locus which encodes a micro RNA cluster known as miR-17/92.

[3] The diagnosis is based on the following clinical findings:[citation needed] There is no known treatment for the disorder, but surgery for malformations, special education, and treatment of hearing loss are important.