Route 13 is a 39 km (24 mi) two-lane uncontrolled access secondary highway traversing the central portion of Prince Edward Island, Canada in a more or less north–south direction between Crapaud and Cavendish.

It passes through a mainly rural area of Prince Edward Island.

A portion of Route 13 (south of Hunter River) is commonly called the "Hopalong Road."

There is an important intersection with Route 2 at Hunter River.

In Cavendish it intersects with Route 6 and terminates at Gulf Shore Road inside Prince Edward Island National Park.