[1] According to his doctor, even though he was trapped for a relatively short time and hopes had originally been higher, subsequent neurological tests showed that after fifty minutes of cardiopulmonary resuscitation in moderate hypothermia, he suffered massive brain damage due to oxygen shortage.

After completing an MBA-programme at INSEAD, Prince Friso worked from 1998 to 2003 as a vice president at Goldman Sachs International in London.

[13] From October 2006, Prince Friso was managing director in the London office of a private investment and advisory firm, Wolfensohn & Company.

[13] Prince Friso was a co-founder of the MRI Centre in Amsterdam and was also a founding shareholder of Wizzair, the largest low-cost airline in Eastern Europe.

[14] Prior to his accident, Prince Friso was working as a chief financial officer for URENCO, a uranium enrichment company.

The Prime Minister Jan Peter Balkenende explained that this was due to discussions with Mabel Wisse Smit in October 2003, when she had admitted that her previous statements about an alleged relationship with Klaas Bruinsma (1953–1991), a known Dutch drug baron, had not been complete and accurate.

Considering that his elder brother King Willem-Alexander has three daughters, Prince Friso's exclusion from the succession was unlikely to have an effect on the monarchy in the Netherlands.

[18] After their marriage, Prince Friso and his wife Princess Mabel set up home in London, in the suburb of Kew.

[19] The couple's first daughter, Countess Emma Luana Ninette Sophie of Orange-Nassau, Jonkvrouwe van Amsberg, was born on 26 March 2005 in London.

Their second daughter, Countess Joanna Zaria Nicoline Milou of Orange-Nassau, Jonkvrouwe van Amsberg, was born on 18 June 2006, also in London.

On 24 February, an Innsbruck medical team announced that the prince had been buried for 25 minutes, followed by a 50-minute CPR to treat his cardiac arrest.

Wolfgang Koller stated that an MRI scan was performed a day earlier revealing little change, however other neurological tests indicated significant damage due to oxygen shortage.

[29] He was buried on 16 August in the Dutch Reformed Cemetery in the hamlet of Lage Vuursche near Drakesteijn Castle, where he had spent his childhood and where Princess Beatrix returned to live in February 2014.