Jesse (Georgian: იესე), also known as 'Isa Khan Gorji (Persian: عیسی خان گرجی, romanized: Isā Xān e Gorji) (c. 1527 – 1580) was a Georgian prince of the royal house of Kakheti, whose career flourished in the service of the Safavid dynasty of Iran and included several years as a governor of Shaki in what is today Azerbaijan.
As a young prince, Jesse was placed by his father at the head of the Georgian auxiliaries requested by the Safavid shah Tahmasp I during his war with the Ottoman Empire (1532–55).
[2] Jesse could have been an unnamed Georgian prince reported by the English explorer Anthony Jenkinson as attending his audience with Shah Tahmasp on 20 November 1562.
But a rival faction, dominated by the Sunni nobles, had Heidar murdered at Kazvin and placed Ismail II on the throne.
According to the 17th-century historian, Iskandar Beg Munshi, 'Isa Khan was imprisoned together with another Georgian, Simon I of Kartli, at Alamut, and was liberated with him by Shah Ismail.