In May 2014, he graduated from Richmond, The American International University in London with a BA degree in Art in Communications.

[3][4][5] At the International Forum on Learning Disabilities, held on 30 January 2016 in Luxembourg, Louis spoke for the first time in public about his struggle with dyslexia.

[6][7] On 12 March 2006, Tessy Antony gave birth to a boy, named Gabriel Michael Louis Ronny de Nassau,[8] who was born at a private Swiss hospital, Clinic des Grangettes, in Geneva.

[11] The couple's second son, Noah Etienne Guillaume Gabriel Matthias Xavier de Nassau, was born on 21 September 2007 at the Grand Duchess Charlotte Maternity Hospital.

Their sons and future children were also given the title "Prince of Nassau" with the style "Royal Highness".

On 6 April 2021, the Grand Ducal Court announced the engagement of Prince Louis to Scarlett-Lauren Sirgue (born on 8 August 1991 in Bordeaux).