In July 1922 it was agreed to introduce a new trophy called the Interregional Championship, which would be held on the road and with the mandatory participation of all regional federations associated with the Spanish FA.

The high economic costs of travel again led to the disappearance of the competition, with a final tournament being played in 1926 with the aim of awarding ownership of the second trophy in dispute, and the champion was Catalonia.

[17][18] The presidents of these two entities, Ruiz Ferry and Julián Olave, eventually reached an agreement in September, which culminated in the creation of the Royal Spanish Football Federation (RFEF).

[22] The opening match between the Catalans and the Castilians was held on 10 May 1915, and was attended by his Majesty King Alfonso XIII, who chatted with the players during the break.

Finally, the teams from the Center and the North met for the decisive game, and the Basques, who were playing without their biggest star Pichichi, managed to go ahead after the break with a goal from Patricio, but the hosts fought back and equalized shortly after courtesy of Santiago Bernabéu.

The title holders, the North Team, did not participate because they were unable to gather all their members due to disagreements that occurred within their own regional federation.

[3] The star of the game was Francisco Cabedo, who scored the competition's first-ever (and only) hat-trick when he netted 4 goals past Centro's goalkeeper Juan de Cárcer, who was thus replaced by Joaquín Pascual for the second leg, which was much more competitive and with a slight local superiority since it found themselves 2–0 up with 20 minute to go, knowing that this win would force a play-off for the title, but Kinké wrecked Centro's hopes with a quick late brace that salvaged a 2–2 draw to the Catalans.

Catalonia's line-up was exactly the same for both games: Gibert; Pakán, Sampere, Salvó I; Casellas, Prat, Kinké, Monistrol; Cabedo, López and Raich.

Centro's line-ups: Cárcer (Pascual); Erice (La Serna), Carruana; E. Aranguren (Tejedor), René Petit (Castell), Quintana; Álvarez, Santiago Bernabéu, E. Uribarri (Pelous), Larrañaga and De Miguel.

[32] Four of these players, Erice, Petit, Álvarez and De Miguel, played for Madrid FC at the 1917 Copa del Rey final.

[34] Centro and Catalonia opened the competition on 9 May 1917, also at O'Donnell's ground, and despite playing away from home, everyone was expecting a comfortable win for the Catalan side, but the Castilian team showed their worth and held the huge favorites to a 2–2 draw,[3] thanks to a brace from Saturno Villaverde.

[35] The decisive clash was played at O'Donnell on the 15 May and Centro showed their quality once again by beating its rival 2–0, with second-half goals from Mieg and Agüero,[36] thus winning the tournament, lifting the trophy, and matching the feats achieved by Norte and Catalonia in the previous two editions of the competition.

[3][2] However, the game, just like the tournament itself, was wrapped in controversy, because at 2–0 down, Catalonia had a goal from Monistrol disallowed in the 70th minute for having scored directly from a corner kick, a circumstance not allowed at the time, and that event led referee Julián Ruete to send off a visiting player (probably Artur Cella) due to the protests, to which the Catalan team left the match in protest.

On the other hand, the incompetence of some federative leaders and the calendar of the competition that allowed the 1917 edition to be played on the same day as the 1917 Copa del Rey final between Madrid FC and Arenas de Getxo - something that prevented the Central Team from having the best players of Madrid and the Basques would have left them without the contribution of their champions, the Arenas Club - had caused the tournament to lose the splendor of the first two editions.

[39] Both games were dominated by the Centro side, with special mention to Cárcer, Machim, Gomar, who trotted a lot, and De Miguel and Sansinenea, who, although obsessed with doing everything by themselves, played brilliantly.

[3] Two years later, the Spanish national team made its official debut at the 1920 Olympic Games in Antwerp, and despite being their first-ever taste of an international major tournament they still managed to win the silver medal.

The second edition of the revived tournament (and sixth overall) was won by Catalonia after beating Centro 3–2 in the replay of the final, after the original game finished in a dramatic 4–4 draw thanks to a last-minute equalizer from Emili Sagi-Barba.

[3] On 5 September 1926, the first leg of this ultimate final was played in El Molinón, ending in a 2–0 win for the Catalans, with both goals being scored by Domingo Broto.

[30][3] Asturian side: Benjamín; Quirós, Trucha; Justo, Menéndez, Corsino; Domingo, Morilla, Herrera, Avilesu and Molinuco.

Oddly, this was the only time Cabedo found the back of the net in the Prince of Asturias Cup, but despite that his 4-goal haul alone makes him one of the all-time top goal scorer in the competition's history.

It's also worth mentioning that some reports list José Luis Zabala as the author of the opening goal of the 1922–23 final on 25 February 1923, which together with his second-half brace makes for another hat-trick in the competition, and one that handed Asturias a 3-1 win over Galicia at Coia.

Although the competition failed to serve as the basis for the formation of a Spanish team, many of the players who participated in this inter-regional competition earned caps for Spain, in fact, a total of 11 players have managed to score at both the Prince of Asturias Cup and at international level for Spain: Patricio, Domingo Acedo, Paulino Alcántara, Manuel Meana, Travieso, Vicente Piera, Juan Monjardín, José Luis Zabala, Josep Samitier, Carmelo and Eduardo Cubells, with Patricio and Alcántara being the only ones who scored in the first phase of the Prince of Asturias Cup (1915–18).