PMC is a major university hospital of the Robert Wood Johnson Medical School of Rutgers University[2] and has a helipad to handle transport of critical patients from and to other hospitals via PennStar, the PennMed air ambulance system[clarification needed].

[5] The new hospital was designed by a joint venture between HOK and RMJM Hiller.

[13] It has no relationship with the fictional Princeton-Plainsboro Teaching Hospital, which was the setting for the medical drama House M.D.

The previous hospital on Witherspoon Street in Princeton was notable for being Albert Einstein's place of death.

[16][17] In 2020–21, U.S. News & World Report ranked the hospital as the ninth-best in New Jersey, 24th-best in the New York City metropolitan area, and "high performing" in the specialty of orthopedics.