Her writings were wide-ranging: she wrote about feminist economics, as well as scientific subjects, in particular the popular eighteenth-century discipline of botany.
[3][2] She was one of several sisters, one of whom, Catherine Bell, married John Gurney of Earlham Hall and had many notable children, the best-known being Elizabeth Fry.
In adult life, Wakefield remained a member of the Society of Friends, and conformed to their religious practices, but did not observe the restrictions on dress or abstinence from amusements.
The surviving daughter, Isabella (3 March 1773 – 17 October 1841), married Joshua Head of Ipswich on 12 September 1794.
Her early publication, Juvenile Anecdotes, Founded on Facts, was successful, and she went on to publish other books of the same nature and of a more advanced character, dealing with science and travel.
By the time she died, Wakefield had written two dozen books, many having appeared in several editions and been translated into foreign languages.
[9] Wakefield was an active philanthropist, promoting education, maternity provision and savings banks for the poor in Tottenham.
In 1792, Wakefield co-founded the School for Industry, which taught girls reading, writing, sewing, knitting and arithmetic.