Pristimantis medemi is a species of frog in the family Strabomantidae.

[2] The species is endemic to Colombia.

The specific name, medemi, is in honor of Federico Medem, who was a Colombian herpetologist of Baltic German descent.

[3] The natural habitats of P. medemi are tropical moist lowland forests, moist montane forests, rivers, plantations, rural gardens, and heavily degraded former forest.

[4] P. medemi is threatened by habitat loss.