Pro-Pain is an American heavy metal band based in New York City, formed in 1991 by vocalist and bassist Gary Meskil and drummer Dan Richardson, both former members of Crumbsuckers.

[5][7] Their second album The Truth Hurts was initially banned due to the sleeve artwork, featuring a picture of a stitched-up woman after an autopsy.

The self-produced album Act of God saw the band signed to Nuclear Blast Records after they had relocated to Sarasota, Florida.

Tom Klimchuck left the band in 2011 due to "unexpected circumstances regarding some potentially serious health issues.

On 3 July 2017, Gary Meskil was the victim of a robbery and attempted murder in Belgium while on tour with Pro-Pain in support of their 2015 album Voice of Rebellion.