It follows the exploits of Junior (Michael Oliver), an adopted orphan boy who deliberately wreaks comedic havoc everywhere he goes.

Amy Yasbeck, who played Ben's wife, Flo, in the first film, also returns, this time as school nurse Annie Young with a daughter named Trixie (Ivyann Schwan) who is also a problem child.

Junior, annoyed at Ben's sudden love interest, retaliates by attempting to draw a mustache on Annie's picture hanging in the hall, only to be foiled by Trixie, the girl whose balloon he popped earlier.

As Annie rushes to take her home, Ben tries to tell her he understands what it is like raising a problem child and thinks they can help one another.

By a chance meeting at a pizza restaurant, Ben, Annie, Junior, and Trixie have dinner together and a good time, even after the food fight the kids start with Peabody and his girlfriend gets them thrown out.

While celebrating her engagement to Ben, she gets icing on her face, which bears a resemblance to foaming at the mouth, a symptom of rabies.

He sabotages her plastic surgery by switching the patient files, resulting in her receiving a gigantic nose – his attempt to make her so ugly that Ben will not marry her.

The "Pizzariffic" scene was filmed at a small, vacant restaurant on Orlando Avenue in Maitland (which became Buca di Beppo two years later).

Napasorn Thai on East Pine Street in Downtown Orlando was used for the Dunmore Bank, as evidenced by the restaurant's unique inlaid corner windows visible in the scene.

The Hyatt Regency Orlando was used as the "Saint Pierre Club" backdrop for Ben and Debbie's date scene.

Dubbing over Junior's use of the term "pussy-whipped" got a PG-13 on appeal, but the studio was still so nervous that, at the last minute, they added the 1947 Woody Woodpecker cartoon Smoked Hams to its theatrical run, to reassure parents that it was suitable for children.

The site's consensus reads: "Crude, rude, puerile, and pointless, Problem Child 2 represents a cynical nadir in family-marketed entertainment".