This mechanism for producing consistent product quality & reducing waste presents a good case for utilising continuous manufacturing technologies.
It would be acceptable to consider that raw materials used to manufacture pharmaceutical products can vary in their attributes e.g. moisture content, crystal structure etc.
With this in mind the PAT drive is to have a dynamic manufacturing process that compensates for variability both in raw materials & equipment to produce a consistent product.
A common problem is picking a complex process and getting mired in the challenge of collecting and analyzing the data.
[8] Fundamental to process analytical technology (PAT) initiatives are the basics of multivariate analysis (MVDA) and design of experiments (DoE).