In the episode, Grand Nagus Zek comes to the station to present Quark with a revised copy of the Rules of Acquisition, which is now a guide for generosity and benevolence.
[3] Grand Nagus Zek, the "financial leader" of the Ferengi race and Quark's idol, arrives on the station and shows Quark and Rom his new project: he has rewritten the Rules of Acquisition, the sacred business proverbs by which the Ferengi live.
This horrifies Quark, because profiteering lies at the heart of Ferengi identity, and the Grand Nagus is supposed to be the paragon.
Doctor Bashir can find no sign of mental or physical illness in Zek, and his uncharacteristic behavior does not appear to be a ruse.
The Prophets, being immaterial creatures who do not experience time linearly, found Zek's obsession with accumulation of material wealth to be strange and adversarial.
Because the Prophets like their privacy and find Ferengi annoying, they release Quark and restore Zek to normal.