The plant is endemic to the southwestern Cape Region of South Africa.

[5] Protea susannae is endemic to the Western Cape province of South Africa.

[5] During the periodic wildfires which pass through its habitat adult plants die, but the seeds can survive such an event.

The seed is stored in the old, dry infructescence which remains persistently attached to the plant.

The plant grows in calcareous and pH-neutral soil at altitudes from sea level to 200 metres.