The project began on December 28, 2006, and ended in June 2008. proteins@home was a large-scale non-profit protein structure prediction project utilizing volunteer computing to perform intensive computations in a small amount of time.

Conversely, the three-dimensional structure is compatible with a large, but limited set of amino acid sequences.

The most expensive step is to build a database of energy functions that describe all these structures.

Surprisingly, this is computationally tractable, because our energy functions are sums over pairs of interactions.

By joining the project, you will help to build the database of energy functions and advance an important area of science with potential biomedical applications.