It is a public hospital (managed partly by an elected council) and serves as the base hospital for Programmatic Area III of Zone VIII of the Santa Fe Ministry of Health.

At the time of its foundation, the hospital was outside the main populated area of the then-small village of Rosario (which had little over 3,000 inhabitants).

the HPR is located in the center of the city (taking up a whole block) and serves an area with a population estimate of 386,000 residents, treating 182,000 people a year, admitting 25 patients a day, and performing 300 surgeries per month.

The hospital also manages 16 primary care centers distributed in the southern part of Rosario.

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