Proxibarbital (Ipronal) is a barbiturate derivative synthesized in 1956.

It has anti-anxiety properties and is, in contrast to most barbiturates, almost without hypnotic action.

[1] It was also used in the treatment of migraine headaches in a similar manner to butalbital.

[2] Valofane isomerises to Proxibarbal in vivo.

This sedative-related article is a stub.