Prudnik County (Polish: powiat prudnicki) is a unit of territorial administration and local government (powiat) in Opole Voivodeship, south-western Poland, on the Czech border.

It came into being on January 1, 1999, as a result of the Polish local government reforms passed in 1998.

Its administrative seat and largest town is Prudnik, which lies 46 kilometres (29 mi) south-west of the regional capital Opole.

The county also contains the towns of Głogówek, lying 21 km (13 mi) east of Prudnik, and Biała, 11 km (7 mi) north-east of Prudnik.

The county covers an area of 571.16 square kilometres (220.5 sq mi).