In 1589, her daughter Anna granted a town charter and the coat of arms of Pruzhany (a blue snake swallowing a baby on a silver shield).

In the mid-19th century, a wealthy Polish landlord, Walenty Szwykowski, laid out a park and built a pretentious palace that houses a museum today, after a restoration.

[2] During World War II, Pruzhany was occupied by the Germans from 26 June 1941 to 17 July 1944.

[3] In Aktion roundups on 28-31 January 1943, the Nazis deported 10,000 Jews of the Pruzhany ghetto to Auschwitz, via Birkenau, where the men, women and children were murdered.

Also, the American actor Mandy Patinkin descends from ancestors from Pruzhany (as well as the nearby shtetl of Drahichyn).