The psalm forms a regular part of Jewish, Catholic, Lutheran, Anglican and other Protestant liturgies.

Moreover, in the Liturgy of the Hours enacted in 1970, the psalm is still recited at Vespers of Sunday's fourth week[9] and evening of the Solemnity of the Epiphany.

Heinrich Schütz composed a metred paraphrase of Psalm 112 in German, "Der ist fürwahr ein selig Mann", SWV 210, for the Becker Psalter, published first in 1628.

The Latin text was set to music by many composers of different nationalities, such as the French Michel-Richard Delalande and André Campra.

Beatus vir is the title of many musical settings for Vespers, such as in Monteverdi's 1610 Vespro della Beata Vergine and 1640 Selva morale e spirituale, Vivaldi's Beatus Vir, and the third movement of Mozart's Vesperae de Dominica (K. 321) and Vesperae solennes de confessore (K. 339).