It has often been set to music, including works in Latin by Michel Richard Delalande, Henry Desmarest and Marc-Antoine Charpentier.

[16] Poetically, if selah is a connection, it is as if David recited his Psalm 3, then paused and began to sing, continuing with his harp.

[18] In the Church of England's Book of Common Prayer, Psalm 4 is appointed to be read on the morning of the first day of the month.

[24] Heinrich Schütz composed a setting of a metred version in German, "Erhör mich, wenn ich ruf zu dir", SWV 100, published in 1628 in the Becker Psalter.

Michel Richard Delalande wrote a great motet (S41) in Latin in 1692 for services celebrated in the royal chapel of Versailles.

Marc-Antoine Charpentier composed around 1689 Cum invocarem exaudivit me, H. 198, for soloists, choir, flutes, strings and continuo.