The psalm forms a regular part of Jewish, Catholic, Lutheran, Anglican and other Protestant liturgies and has often been set to music.

[clarification needed] The psalm begins with a recounting of the days of old in verse 2, that God had driven out the nations and planted the Israelites, placing this well after the periods of conquest and the judges.

The writer of the Explaining the Book commentary notes that neither Charles Spurgeon nor Matthew Henry felt that they could be clear about the setting for this psalm.

[9] Verse 22 is referenced by the Apostle Paul in the New Testament book "the Epistle to the Romans 8:36"[13] in the context of realities that can make Christians think that they are separated from God's love.

In the Church of England's Book of Common Prayer, this psalm is appointed to be read on the morning of the ninth day of the month.

[citation needed] Heinrich Schütz wrote a setting of a paraphrase of Psalm 44 in German, "Wir haben, Herr, mit Fleiß gehört", SWV 141, for the Becker Psalter, published first in 1628.