Unknown parameter name Psalmotoxin (PcTx1) is a spider toxin from the venom of the Trinidad tarantula Psalmopoeus cambridgei.

Psalmotoxin is a toxin produced in the venom glands of the South American tarantula Psalmopoeus cambridgei.

Many ion channel effectors from snail, spider, and scorpion venoms share a similar ICK structure, although they possess very different pharmalogical profiles.

Expression of ASIC1a in the central nervous system relates to the involvement of ASIC1a in higher brain functions, such as learning, memory and fear conditioning.

[14] The role of psalmotoxin in prey capture and the importance of ASIC1a channels as targets of venom components remains unclear.

Recently, it has been shown that activation of ASIC1a during the acidosis accompanying brain ischemia leads to significant Ca2+ influx, which contributes to neuronal cell death.

[17] As ASIC's play a role in nociception, psalmotoxin could be helpful in designing new analgesic drugs acting directly against pain at the nociceptor level.