[1] The law seeks to make manufacturers test and prove their products are low-risk before they can be sold.

[2][3][4] Testing is expected to cost manufacturers $1 to 2 million dollars.

[5] A later addition to the law, Section 4(f), specified that "animals must not be used in trials for the purposes of assessing whether a psychoactive product should be approved."

[7] The Act was brought in as a reaction to widespread concerns[8] over the 2005 deregulation, or decriminalisation, of selling psychoactive substances in New Zealand with the introduction of section 62 in the Misuse of Drugs Amendment Act 2005 and the Misuse of Drugs (Restricted Substances) Regulations 2008.

[9] These laws made psychoactive substances such as party pills and legal highs available in New Zealand in a relatively new experimental market aimed at decriminalising the production and sale of recreational drugs.