It consists of psychopathological complex of symptoms that are caused by organic brain disorders that involve a reduction in memory and intellect.
There are many causes, including cerebrovascular diseases, CNS damages to traumatic brain injury, intoxication, exposure to organic solvents such as toluene, chronic metabolic disorders, tumors and abscesses of the brain, encephalitis, and can also be found in cases of diseases accompanied by convulsive seizures.
Patients with psychoorganic syndrome often complain about headaches, dizziness, unsteadiness when walking, poor tolerance to the heat, stuffiness, atmospheric pressure changes, loud sounds, neurological symptoms.
[3] Psycho-organic syndrome is typically diagnosed in individuals following 5–10 years of consistent exposure to chemicals like xylene, toluene, and styrene, which are generally found in paint, plastic and degreasing products.
[4]"In pathological findings, focal or diffuse signs of atrophy without inflammation or severe vascular insufficiency are present.
[6] Along with occupational and environmental evaluation, a neurological exam, ECHO, EEG, CT-San, and X-ray of the brain may be conducted to determine disorder.
CT scan or MRI can confirm dementia via observation of ventricular dilation and cortical substance degeneration.
[4] Pick's disease can be confirmed via CT scan or MRI with atrophy of frontal and temporal lobe roots.
[9] POS was suggested to be associated with long term and high level solvent exposure in early studies conducted in Scandinavia.
In a 2007 clinical study conducted in Sweden on 128 subjects who had constant high exposure to solvents in their work environments, a definite link to POS was unable to be determined.