Ptolemaida (Greek: Πτολεμαΐδα, romanized: Ptolemaïda, Katharevousa: Πτολεμαΐς, Ptolemaïs) is a town and a former municipality in Kozani regional unit, Western Macedonia, Greece.

The modern name Ptolemaida was introduced by decree on January 20, 1927, honoring Ptolemy I Soter, son of Lagus, comrade-in-arms of Alexander the Great and founder of the Ptolemaic dynasty, and his daughter Ptolemaïs, who are said to originate from that region.

[6] Associated Press reporter Costas Kantouris describes the item as a "flat, roughly ring-shaped [which] probably had religious significance and would have been worn on a necklace by a prominent member of society.

"[6] Lately in the lake Zazari near Ptolemaida there were found 16 houses that belong in the Neolithic era due to archaeologists.

The Land of the Chords and the whole region of Eordea was fully incorporated into Macedon under Philip II and later his successor Alexander.

Two of the six generals of Alexander the Great, Ptolemy I Soter, founder of the Ptolemaic Kingdom, and Aristones are claimed to hail from Eordaia.

There were many clashes during the long struggle between the Macedonians and the Romans who tried to enter the basin of Eordea and promote it into mainland Greece, but also because the area was a focal point as a secondary road passed through it.

[citation needed] Before 1360, large numbers of nomad shepherds, or Yörüks, from the district of Konya, in Asia Minor, had settled in Macedonia; their descendants were known as Konariotes.

After the establishment of the feudal system in 1397, many of the Seljuk noble families came over from Asia Minor; their descendants may be recognized among the Beys or Muslim landowners around Kayılar.

[3] A low birth rate, the exhaustion of the male population by military service, and a large mortality from epidemics brought about a decline which has lately been hastened by emigration.

In the 1970s, Greece's largest coal-fired power plants were built in the region of Ptolemaida, these increased pollution and it is expected these will be shut down by the year 2028.

The most important lignite deposits in Greece are located in the north of the country at Ptolemais-Amynteon and Florina (approximately 1.5 billion tonnes) which contribute around 80% of national production.

The School of Health Sciences of University of Western Macedonia with two departments (Occupational Therapy and Midwifery) based in the city.

[8] The city, situated in the middle of the Eordaia plain of Western Macedonia, has a humid subtropical climate (Cfa) with continental (Dfa) influences.