Publius Valerius Eutychianus Comazon (died after 222) was a Roman general and ally of emperor Elagabalus.
Comazon began his career as an ordinary army recruit under the Emperor Commodus, whom he served as a soldier in the province of Thrace.
In the year 218 he commanded the Legio II Parthica, which was temporarily stationed in Apamea in Syria.
Upon the accession of Macrinus as emperor in 217, Comazon orchestrated a revolt among the members of Legio III Gallica to help secure the throne for Elagabalus, who was tied to the Severan dynasty.
Elagabalus proved to be a highly unpopular ruler, and after barely four years in office, he was murdered by members of the Praetorian Guard who proclaimed his cousin Alexander Severus emperor in his place.